KRP650
连接粘附分子A, Junctional adhesion molecule A , JAM-A, Junctional adhesion molecule 1, JAM-1, Platelet F11 receptor, Platelet adhesion molecule 1, PAM-1, CD antigen CD321, JAM1, JCAM, UNQ264/PRO301, Junctional adhesion molecule A
| Catalog Number | KRP650 |
| Alias | 连接粘附分子A, Junctional adhesion molecule A , JAM-A, Junctional adhesion molecule 1, JAM-1, Platelet F11 receptor, Platelet adhesion molecule 1, PAM-1, CD antigen CD321, JAM1, JCAM, UNQ264/PRO301, Junctional adhesion molecule A |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Human F11R(Ser28 - Ala242) |
| Molecular Name | F11R |
| Product Introduction | 连接粘附分子A在细胞间的粘附和信号传递中起重要作用，影响免疫反应。。 |
| Molecular Weight | 60-65 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥90% |
| SDS-PAGE | |
| Purification | Affinity Purification |
| Uniprot ID | Q9Y624-1 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity). Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (PubMed:11812992). Involved in platelet activation (PubMed:10753840). {ECO:0000250|UniProtKB:O88792, ECO:0000269|PubMed:10753840, ECO:0000269|PubMed:11489913, ECO:0000269|PubMed:11812992}.; (Microbial infection) Acts as a receptor for Mammalian reovirus sigma-1. {ECO:0000269|PubMed:11239401}.; (Microbial infection) Acts as a receptor for Human Rotavirus strain Wa. {ECO:0000269|PubMed:25481868}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | 联系销售经理获得最新活性数据 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
是的，根据蛋白的性质，有些蛋白需要特定的缓冲液、添加剂（如甘油、离子强度调节剂等）来保持其稳定性。
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