KRP638
基质金属蛋白酶17, Matrix metalloproteinase-17 , MMP-17, EC 3.4.24.-, Membrane-type matrix metalloproteinase 4, MT-MMP 4, MTMMP4, Membrane-type-4 matrix metalloproteinase, MT4-MMP, MT4MMP, MT4MMP, Matrix metalloproteinase-17
| Catalog Number | KRP638 |
| Alias | 基质金属蛋白酶17, Matrix metalloproteinase-17 , MMP-17, EC 3.4.24.-, Membrane-type matrix metalloproteinase 4, MT-MMP 4, MTMMP4, Membrane-type-4 matrix metalloproteinase, MT4-MMP, MT4MMP, MT4MMP, Matrix metalloproteinase-17 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Human MMP17(Ala39-Ser531(Arg125Pro，Ala182Thr)) |
| Molecular Name | MMP17 |
| Product Introduction | 基质金属蛋白酶17参与细胞外基质重塑，影响组织发育和修复。。 |
| Molecular Weight | 56-65 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥90% |
| Purification | Affinity Purification |
| Uniprot ID | Q9ULZ9-1 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its ability to cleave a fluorogenic peptide substrate Mca-PLAQAV-Dpa-RSSSR-NH2. The specific activity is >150 pmol/min/μg, as measured underthe described condition. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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