| Catalog Number | KRP606 |
| Alias | 基质细胞外磷酸糖蛋白, Matrix extracellular phosphoglycoprotein , Osteoblast/osteocyte factor 45, OF45, Osteoregulin, Matrix extracellular phosphoglycoprotein |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Human MEPE(Pro18-Asp525& Phe20-Asp525 &Gln21-Asp525) |
| Molecular Name | MEPE |
| Product Introduction | 基质细胞外磷酸糖蛋白调节骨质和结缔组织的重建和修复。。 |
| Molecular Weight | 82 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥90% |
| Purification | Affinity Purification |
| Uniprot ID | Q9NQ76 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Promotes renal phosphate excretion and inhibits intestinal phosphate absorption (PubMed:14962809, PubMed:19005008). Promotes bone mineralization by osteoblasts and cartilage mineralization by chondrocytes (PubMed:18162525, PubMed:19998030, PubMed:22766095). Regulates the mineralization of the extracellular matrix of the craniofacial complex, such as teeth, bone and cartilage (By similarity). Promotes dental pulp stem cell proliferation and differentiation (PubMed:22341070). {ECO:0000250|UniProtKB:Q8K4L6, ECO:0000269|PubMed:14962809, ECO:0000269|PubMed:18162525, ECO:0000269|PubMed:19005008, ECO:0000269|PubMed:19998030, ECO:0000269|PubMed:22341070, ECO:0000269|PubMed:22766095}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its ability to induce adhesion of ATDC5 mouse chondrogenic cells.rhMEPE, immobilized at 2 µg/mL (100 µL/well), can induce more than 60% of ATDC5 cell adhesion. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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