Canine IL-13 Protein, No tag_天津卡梅德科技发展有限公司

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Canine IL-13 Protein, No tag

Canine IL-13 Protein, No tag

产品编号

KRP599

别名

白细胞介素-13, Interleukin-13 , IL-13, Interleukin-13 (IL-13)

规格

20ug
50ug
100ug
200ug
1mg

DATASHEET MSDS

立即询价加入询价列表大包装定制

产品介绍

Alias	白细胞介素-13, Interleukin-13 , IL-13, Interleukin-13 (IL-13)
Catalog Number	KRP599
Molecular Name	IL13
Molecular Weight	10 kDa & 11 kDa
Size	20ug, 50ug, 100ug, 200ug, 1mg
Concentration	联系销售经理获得最新批次的浓度
Purity	≥95%
Product Description	Canine IL13(19-131 aa)
Storage Condition	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation	＜1.0EU/ug
Shipping Condition	This product is shipped on ice packs or dry ice.
Background	Cytokine that plays important roles in allergic inflammation and immune response to parasite infection. Synergizes with IL2 in regulating interferon-gamma synthesis. Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells (By similarity). Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1 (By similarity). Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF-alpha through a mechanism that partially involves suppression of NF-kappa-B (By similarity). Also functions on nonhematopoietic cells, including endothelial cells where it induces vascular cell adhesion protein 1/VCAM1, which is important in the recruitment of eosinophils. Exerts its biological effects through its receptors which comprises the IL4R chain and the IL13RA1 chain, to activate JAK1 and TYK2, leading to the activation of STAT6. Aside from IL13RA1, another receptor IL13RA2 acts as a high affinity decoy for IL13 and mediates internalization and depletion of extracellular IL13 (By similarity). {ECO:0000250\|UniProtKB:P20109, ECO:0000250\|UniProtKB:P35225, ECO:0000250\|UniProtKB:P42203}.
Species	Canine
Purification	Affinity Purification
Endotoxin	Supplied in PBS
Biological Activity	Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 forthis effect is 0.75-3.75 ng/mL.
Uniprot ID	Q9N0W9
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。
Display Peptides	E. coli

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