Recombinant Human TwistedGastrulation/TSG Protein, C-His Tag
-
产品编号
KRP578
-
别名
扭曲原肠胚形成蛋白同源物1, Twisted gastrulation protein homolog 1, TSG, PSEC0250,
-
规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
Alias | 扭曲原肠胚形成蛋白同源物1, Twisted gastrulation protein homolog 1, TSG, PSEC0250, |
Catalog Number | KRP578 |
Molecular Name | TWSG1 |
Molecular Weight | 35-43 kDa |
Size | 20ug, 50ug, 100ug, 200ug, 1mg |
Concentration | 联系销售经理获得最新批次的浓度 |
Purity | ≥95% |
Product Description | Human TWSG1(Met1-Phe223) |
Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
Formulation | < 0.1 EU per ug |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Background | May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity). {ECO:0000250}. |
Species | Human |
Purification | Affinity Purification |
Endotoxin | Supplied in PBS |
Biological Activity | Measured by its ability to inhibit BMP-6-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 forthis effect is 4-16 μg/mL in the presence of 100 ng/mL of Recombinant Human BMP-6. |
Uniprot ID | Q9GZX9 |
Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |
Display Peptides | HEK293F Cells |