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Recombinant Human TwistedGastrulation/TSG Protein, C-His Tag

Recombinant Human TwistedGastrulation/TSG Protein, C-His Tag

产品编号

KRP578

别名

扭曲原肠胚形成蛋白同源物1, Twisted gastrulation protein homolog 1, TSG, PSEC0250,

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberKRP578
Alias扭曲原肠胚形成蛋白同源物1, Twisted gastrulation protein homolog 1, TSG, PSEC0250,
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionHuman TWSG1(Met1-Phe223)
Molecular NameTWSG1
Product Introduction扭曲原肠胚形成蛋白同源物1在胚胎发育中起重要作用,尤其是在组织重塑和神经发育中。。
Molecular Weight35-43 kDa
Expression SystemHEK293F Cells
SpeciesHuman
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
PurificationAffinity Purification
Uniprot IDQ9GZX9
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationSupplied in PBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundMay be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity). {ECO:0000250}.
Endotoxin< 0.1 EU per ug
Biological ActivityMeasured by its ability to inhibit BMP-6-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 forthis effect is 4-16 μg/mL in the presence of 100 ng/mL of Recombinant Human BMP-6.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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