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Recombinant Human TwistedGastrulation/TSG Protein, C-His Tag

Recombinant Human TwistedGastrulation/TSG Protein, C-His Tag

产品编号

KRP578

别名

扭曲原肠胚形成蛋白同源物1, Twisted gastrulation protein homolog 1, TSG, PSEC0250,

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Alias扭曲原肠胚形成蛋白同源物1, Twisted gastrulation protein homolog 1, TSG, PSEC0250,
Catalog NumberKRP578
Molecular NameTWSG1
Molecular Weight35-43 kDa
Size20ug, 50ug, 100ug, 200ug, 1mg
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
Product DescriptionHuman TWSG1(Met1-Phe223)
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation< 0.1 EU per ug
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundMay be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity). {ECO:0000250}.
SpeciesHuman
PurificationAffinity Purification
EndotoxinSupplied in PBS
Biological ActivityMeasured by its ability to inhibit BMP-6-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 forthis effect is 4-16 μg/mL in the presence of 100 ng/mL of Recombinant Human BMP-6.
Uniprot IDQ9GZX9
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。
Display PeptidesHEK293F Cells

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