KRP575
血小板衍生生长因子D, Platelet-derived growth factor D , PDGF-D, Iris-expressed growth factor, Spinal cord-derived growth factor B, SCDGF-B, [Cleaved into: Platelet-derived growth factor D, latent form , PDGFD latent form, ; Platelet-derived growth factor D, recept
| Alias | 血小板衍生生长因子D, Platelet-derived growth factor D , PDGF-D, Iris-expressed growth factor, Spinal cord-derived growth factor B, SCDGF-B, [Cleaved into: Platelet-derived growth factor D, latent form , PDGFD latent form, ; Platelet-derived growth factor D, recept |
| Catalog Number | KRP575 |
| Molecular Name | PDGFD |
| Molecular Weight | 19 kDa |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| Product Description | Human PDGFD(250-370 aa) |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | < 0.1 EU per ug |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix (By similarity). {ECO:0000250, ECO:0000269|PubMed:11331881, ECO:0000269|PubMed:15271796}. |
| Species | Human |
| Purification | Affinity Purification |
| Endotoxin | Supplied in PBS |
| Biological Activity | Measured in a cell proliferation assay using NR6R‑3T3 mouse fibroblast cells. The ED50 for this effect is 15‑75 ng/mL in a fluorometric assay using the redox sensitive dye, Resazurin and 2-5 ng/mL when measured by 3Hthymidine incorporation. |
| Uniprot ID | Q9GZP0-1 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Display Peptides | HEK293F Cells |
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