KRP575
血小板衍生生长因子D, Platelet-derived growth factor D , PDGF-D, Iris-expressed growth factor, Spinal cord-derived growth factor B, SCDGF-B, [Cleaved into: Platelet-derived growth factor D, latent form , PDGFD latent form, ; Platelet-derived growth factor D, recept
| Catalog Number | KRP575 |
| Alias | 血小板衍生生长因子D, Platelet-derived growth factor D , PDGF-D, Iris-expressed growth factor, Spinal cord-derived growth factor B, SCDGF-B, [Cleaved into: Platelet-derived growth factor D, latent form , PDGFD latent form, ; Platelet-derived growth factor D, recept |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Human PDGFD(250-370 aa) |
| Molecular Name | PDGFD |
| Product Introduction | 血小板衍生生长因子D参与血管生成与伤口愈合过程，促进细胞迁移与增殖。。 |
| Molecular Weight | 19 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| Purification | Affinity Purification |
| Uniprot ID | Q9GZP0-1 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix (By similarity). {ECO:0000250, ECO:0000269|PubMed:11331881, ECO:0000269|PubMed:15271796}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured in a cell proliferation assay using NR6R‑3T3 mouse fibroblast cells. The ED50 for this effect is 15‑75 ng/mL in a fluorometric assay using the redox sensitive dye, Resazurin and 2-5 ng/mL when measured by 3Hthymidine incorporation. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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