KRP539
白细胞介素-22受体亚单位α-2, Interleukin-22 receptor subunit alpha-2 , IL-22 receptor subunit alpha-2, IL-22R-alpha-2, IL-22RA2, Cytokine receptor class-II member 10, Cytokine receptor family 2 member 10, CRF2-10, Cytokine receptor family type 2, soluble 1, CRF2-S1,
| Catalog Number | KRP539 |
| Alias | 白细胞介素-22受体亚单位α-2, Interleukin-22 receptor subunit alpha-2 , IL-22 receptor subunit alpha-2, IL-22R-alpha-2, IL-22RA2, Cytokine receptor class-II member 10, Cytokine receptor family 2 member 10, CRF2-10, Cytokine receptor family type 2, soluble 1, CRF2-S1, |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Human IL22RA2(22-231 aa) |
| Molecular Name | IL22RA2 |
| Product Introduction | 白细胞介素-22受体亚单位α-2介导免疫反应和组织修复。。 |
| Molecular Weight | 46-53 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | Q969J5-2 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses.; Isoform 1 may play a role in establishing and maintaining successful pregnancy. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its ability to inhibit IL-22-induced IL-10 secretion by COLO 205 human colorectal adenocarcinoma cells. The ED50 forthis effect is typically 1-5 ng/mL in the presence of 1 ng/mL of Recombinant Human IL-22. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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