KRP521
白细胞介素-17受体D, Interleukin-17 receptor D , IL-17 receptor D, IL-17RD, IL17Rhom, Interleukin-17 receptor-like protein, Sef homolog, hSef, IL17RLM, SEF, UNQ6115/PRO20026, Interleukin-17 receptor D
| Alias | 白细胞介素-17受体D, Interleukin-17 receptor D , IL-17 receptor D, IL-17RD, IL17Rhom, Interleukin-17 receptor-like protein, Sef homolog, hSef, IL17RLM, SEF, UNQ6115/PRO20026, Interleukin-17 receptor D |
| Catalog Number | KRP521 |
| Molecular Name | IL17RD |
| Molecular Weight | 55-63 kDa |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Product Description | Human IL17RD(27-299 aa) |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | < 0.1 EU per ug |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation (PubMed:12807873, PubMed:12958313). Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK (PubMed:15239952). Mediates JNK activation and may be involved in apoptosis (By similarity). May inhibit FGF-induced FGFR1 tyrosine phosphorylation (By similarity). Might have a role in the early stages of fate specification of GnRH-secreting neurons (By similarity). Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells (By similarity). {ECO:0000250|UniProtKB:Q8JZL1, ECO:0000269|PubMed:12807873, ECO:0000269|PubMed:12958313, ECO:0000269|PubMed:15239952}. |
| Species | Human |
| Purification | Affinity Purification |
| Endotoxin | Supplied in PBS |
| Biological Activity | 联系销售经理获得最新活性数据 |
| Uniprot ID | Q8NFM7 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Display Peptides | HEK293F Cells |
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