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Recombinant Mouse IL-31RA Protein, C-hFc and His tag

Recombinant Mouse IL-31RA Protein, C-hFc and His tag

产品编号

KRP511

别名

白细胞介素-31受体亚单位alpha, Interleukin-31 receptor subunit alpha , IL-31 receptor subunit alpha, IL-31R subunit alpha, IL-31R-alpha, IL-31RA, GLM-R, mGLM-R, Gp130-like monocyte receptor, Gp130-like receptor, Novel cytokine receptor 10, NR10, ZcytoR17, Glmr, Inte

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Alias白细胞介素-31受体亚单位alpha, Interleukin-31 receptor subunit alpha , IL-31 receptor subunit alpha, IL-31R subunit alpha, IL-31R-alpha, IL-31RA, GLM-R, mGLM-R, Gp130-like monocyte receptor, Gp130-like receptor, Novel cytokine receptor 10, NR10, ZcytoR17, Glmr, Inte
Catalog NumberKRP511
Molecular NameIl31ra
Molecular Weight90-103 kDa
Size20ug, 50ug, 100ug, 200ug, 1mg
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
SDS-PAGE
Product DescriptionMouse Il31ra(Val19-Ser503)
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation< 0.1 EU per ug
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundAssociates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity (PubMed:15184896). Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1 (PubMed:24373353). Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro (PubMed:17379091). {ECO:0000269|PubMed:15184896, ECO:0000269|PubMed:17379091, ECO:0000269|PubMed:24373353}.
SpeciesMouse
PurificationAffinity Purification
EndotoxinSupplied in PBS
Biological ActivityMeasured by its binding ability in a functional ELISA. When Recombinant Mouse IL‑31 RA Fc Chimera is immobilized at 5 µg/mL (100 µL/well), Recombinant Mouse IL‑31 binds with an ED50 of 0.9-5.4 μg/mL.
Uniprot IDQ8K5B1-1
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。
Display PeptidesHEK293F Cells

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