Recombinant Human Cerebellin-2 Protein, N-His Tag_天津卡梅德科技发展有限公司

Recombinant Human Cerebellin-2 Protein, N-His Tag

产品编号

KRP506

别名

小脑素2, Cerebellin-2, UNQ1892/PRO4338, Cerebellin-2

规格

20ug
50ug
100ug
200ug
1mg

DATASHEET MSDS

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产品介绍

Catalog Number	KRP506
Alias	小脑素2, Cerebellin-2, UNQ1892/PRO4338, Cerebellin-2
Size	20ug, 50ug, 100ug, 200ug, 1mg
Product Description	Human CBLN2(50-224 aa)
Molecular Name	CBLN2
Product Introduction	小脑素2在小脑中发挥作用，影响神经细胞发育和修复。。
Molecular Weight	25-35 kDa
Expression System	HEK293F Cells
Species	Human
Concentration	联系销售经理获得最新批次的浓度
Purity	≥90%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	Q8IUK8
Storage Condition	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation	Supplied in PBS
Shipping Condition	This product is shipped on ice packs or dry ice.
Background	Acts as a synaptic organizer in specific subsets of neurons in the brain. Essential for long-term maintenance but not establishment of excitatory synapses. Functions as part of a trans-synaptic complex by binding to postsynaptic GRID1 and presynaptic neurexins. This interaction helps regulate the activity of NMDA and AMPA receptors at hippocampal synapses without affecting synapse formation. NRXN1B-CBLN2-GRID1 complex transduce presynaptic signals into postsynaptic NMDAR response. NRXN3B-CBLN2-GRID1 complex transduce presynaptic signals into postsynaptic AMPAR response. {ECO:0000250\|UniProtKB:Q8BGU2}.
Endotoxin	< 0.1 EU per ug
Biological Activity	Measured by its binding ability in a functional ELISA. When Recombinant Human Cerebellin-2 is coated at 5 μg/mL, biotinylated recombinantrat NRXN-1 beta binds with an apparent KD <1.5 nM. Measured by its ability to enhance neurite outgrowth of E16- E18 ra
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。