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Recombinant Human IL28RA Protein, C-hFc and His tag

Recombinant Human IL28RA Protein, C-hFc and His tag

产品编号

KRP505

别名

干扰素λ受体1, Interferon lambda receptor 1 , IFN-lambda receptor 1, IFN-lambda-R1, Cytokine receptor class-II member 12, Cytokine receptor family 2 member 12, CRF2-12, Interleukin-28 receptor subunit alpha, IL-28 receptor subunit alpha, IL-28R-alpha, IL-28RA,

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Alias干扰素λ受体1, Interferon lambda receptor 1 , IFN-lambda receptor 1, IFN-lambda-R1, Cytokine receptor class-II member 12, Cytokine receptor family 2 member 12, CRF2-12, Interleukin-28 receptor subunit alpha, IL-28 receptor subunit alpha, IL-28R-alpha, IL-28RA,
Catalog NumberKRP505
Molecular NameIFNLR1
Molecular Weight65-75 kDa
Size20ug, 50ug, 100ug, 200ug, 1mg
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
SDS-PAGE
Product DescriptionHuman IFNLR1(21-228 aa)
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation< 0.1 EU per ug
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundThe IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, and reproductive tracts. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. {ECO:0000269|PubMed:12469119, ECO:0000269|PubMed:12483210, ECO:0000269|PubMed:12521379}.
SpeciesHuman
PurificationAffinity Purification
EndotoxinSupplied in PBS
Biological ActivityMeasured by its binding ability in a functional ELISA. In a 100 μL reaction mixture containing rhIL-28 R alpha /Fc Chimera at 1 μg/mL and rhIL- 28A dilutions at 1- 1000 ng/mL, the concentration of rhIL-28A that produces 50% of the optimal binding response
Uniprot IDQ8IU57
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。
Display PeptidesHEK293F Cells

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