KRP496
T细胞活化抑制因子1, V-set domain-containing T-cell activation inhibitor 1 , B7 homolog 4, B7-H4, B7h.5, Immune costimulatory protein B7-H4, Protein B7S1, T-cell costimulatory molecule B7x, B7H4, UNQ659/PRO1291, V-set domain-containing T-cell activation inhibitor
| Alias | T细胞活化抑制因子1, V-set domain-containing T-cell activation inhibitor 1 , B7 homolog 4, B7-H4, B7h.5, Immune costimulatory protein B7-H4, Protein B7S1, T-cell costimulatory molecule B7x, B7H4, UNQ659/PRO1291, V-set domain-containing T-cell activation inhibitor |
| Catalog Number | KRP496 |
| Molecular Name | VTCN1 |
| Molecular Weight | 45-60 kDa |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Product Description | Human VTCN1(29-258 aa) |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | < 0.1 EU per ug |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation. {ECO:0000250|UniProtKB:Q7TSP5, ECO:0000269|PubMed:15878339, ECO:0000269|PubMed:16606666, ECO:0000269|PubMed:17509674, ECO:0000269|PubMed:17875732}. |
| Species | Human |
| Purification | Affinity Purification |
| Endotoxin | Supplied in PBS |
| Biological Activity | Immobilized HUMAN B7- H4/VTCN1/VISTA at 1 μg/mL (100 μL/well) can bind B7-H4/VTCN1 antibody with a linearrange of 0.2-22 ng/mL. |
| Uniprot ID | Q7Z7D3-1 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Display Peptides | HEK293F Cells |
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