Recombinant Mouse Kitl Protein, C-hFc and His tag_天津卡梅德科技发展有限公司

Recombinant Mouse Kitl Protein, C-hFc and His tag

产品编号

KRP492

别名

Kit配体, Kit ligand , Hematopoietic growth factor KL, Mast cell growth factor, Stem cell factor, c-Kit ligand, Kit ligand

规格

20ug
50ug
100ug
200ug
1mg

DATASHEET MSDS

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产品介绍

Catalog Number	KRP492
Alias	Kit配体, Kit ligand , Hematopoietic growth factor KL, Mast cell growth factor, Stem cell factor, c-Kit ligand, Kit ligand
Size	20ug, 50ug, 100ug, 200ug, 1mg
Product Description	Mouse Kitl(Lys26-Ala189)
Molecular Name	Kitl
Product Introduction	Kit配体通过影响细胞增殖和分化，调节免疫反应。。
Molecular Weight	18-38 kDa
Expression System	HEK293F Cells
Species	Mouse
Concentration	联系销售经理获得最新批次的浓度
Purity	≥95%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	Q78ED8
Storage Condition	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation	Supplied in PBS
Shipping Condition	This product is shipped on ice packs or dry ice.
Background	Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins. {ECO:0000256\|ARBA:ARBA00057397}.
Endotoxin	< 0.1 EU per ug
Biological Activity	Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is 0.5-1.0 ng/mL, corresponding to a specific activity of 1.0×106-2.0×106 units/mg.
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。