| Catalog Number | KRP491 |
| Alias | 免疫球蛋白样结构域含受体2, Immunoglobulin-like domain-containing receptor 2 , Angulin-3, C1orf32, Immunoglobulin-like domain-containing receptor 2 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Human ILDR2(21-186 aa) |
| Molecular Name | ILDR2 |
| Product Introduction | 免疫球蛋白样结构域含受体2参与调节肿瘤生长，影响肿瘤免疫逃逸机制。。 |
| Molecular Weight | 47-52 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE | |
| Purification | Affinity Purification |
| Uniprot ID | Q71H61 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | May be involved in ER stress pathways with effects on lipid homeostasis and insulin secretion. With ILDR1 and LSR, involved in the maintain of the epithelial barrier function through the recruitment of MARVELD2/tricellulin to tricellular tight junctions (By similarity). Also functions as a B7-like protein family member expressed on immune cells and inflamed tissue and with T-cell inhibitory activity (PubMed:29431694). In the inner ear, may regulate alternative pre-mRNA splicing via binding to TRA2A, TRA2B and SRSF1 (By similarity). {ECO:0000250|UniProtKB:B5TVM2, ECO:0000269|PubMed:29431694}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its ability to inhibit anti-CD3 antibody induced IFNgamma secretion by human peripheral blood mononuclear cells (PBMC). The ED50 for this effect is 1-6 μg/mL. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
可以通过SDS-PAGE、透射电子显微镜（TEM）或活性测试来检测蛋白是否变性或降解。
已表达的蛋白可以用于酶学分析、结构研究、免疫检测、细胞培养实验等多种实验。
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