Alias | C型凝集素结构域家族9成员A, C-type lectin domain family 9 member A , CD antigen CD370, UNQ9341/PRO34046, C-type lectin domain family 9 member A |
Catalog Number | KRP487 |
Molecular Name | CLEC9A |
Molecular Weight | 55-65 kDa |
Size | 20ug, 50ug, 100ug, 200ug, 1mg |
Concentration | 联系销售经理获得最新批次的浓度 |
Purity | ≥95% |
SDS-PAGE |  |
Product Description | Human CLEC9A(57-241 aa) |
Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
Formulation | < 0.1 EU per ug |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Background | Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner. {ECO:0000269|PubMed:18497879, ECO:0000269|PubMed:22483802}. |
Species | Human |
Purification | Affinity Purification |
Endotoxin | Supplied in PBS |
Biological Activity | Measured by flow cytometry forits ability to bind a ligand expressed in FasLtreated mouse B cells. At 100 ng/mL, >50% of necrotic cells bind to Recombinant Human CLEC9a. |
Uniprot ID | Q6UXN8 |
Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |
Display Peptides | HEK293F Cells |