KRP483
白细胞介素-27受体亚单位alpha, Interleukin-27 receptor subunit alpha , IL-27 receptor subunit alpha, IL-27R subunit alpha, IL-27R-alpha, IL-27RA, Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor, TCCR, ZcytoR1, CRL1, TCCR, WSX1, UNQ
| Catalog Number | KRP483 |
| Alias | 白细胞介素-27受体亚单位alpha, Interleukin-27 receptor subunit alpha , IL-27 receptor subunit alpha, IL-27R subunit alpha, IL-27R-alpha, IL-27RA, Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor, TCCR, ZcytoR1, CRL1, TCCR, WSX1, UNQ |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Human IL27RA(34-516aa) |
| Molecular Name | IL27RA |
| Product Introduction | 白细胞介素-27受体亚单位alpha通过与IL-27受体结合，调节免疫反应和细胞增殖。。 |
| Molecular Weight | 100-110 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| Purification | Affinity Purification |
| Uniprot ID | Q6UWB1 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Receptor for IL27. Requires IL6ST/GP130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Acts as a receptor for the neuroprotective peptide humanin as part of a complex with IL6ST/GP130 and CNTFR (PubMed:19386761). Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms. {ECO:0000269|PubMed:14764690, ECO:0000269|PubMed:19386761}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its ability to inhibit IL- 27 anti-viral activity using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus. The ED50 forthis effect is 0.75‑4.5 µg/mL. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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