| Alias | 内质网氨肽酶2, Endoplasmic reticulum aminopeptidase 2 , EC 3.4.11.-, Leukocyte-derived arginine aminopeptidase, L-RAP, LRAP, Endoplasmic reticulum aminopeptidase 2 |
| Catalog Number | KRP478 |
| Molecular Name | ERAP2 |
| Molecular Weight | 122 kDa |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥90% |
| SDS-PAGE |  |
| Product Description | Human ERAP2(56-960 aa) |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | < 0.1 EU per ug |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys. {ECO:0000269|PubMed:12799365, ECO:0000269|PubMed:15908954, ECO:0000269|PubMed:16286653}. |
| Species | Human |
| Purification | Affinity Purification |
| Endotoxin | Supplied in PBS |
| Biological Activity | Measured by its ability to cleave the fluorogenic peptide substrate, Arg-7-amido-4- methylcoumarin (Arg-AMC). The specific activity is >50 pmol/min/µg, as measured underthe described conditions. |
| Uniprot ID | Q6P179 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Display Peptides | HEK293F Cells |
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