| Catalog Number | KRP475 |
| Alias | 细胞毒性T淋巴细胞蛋白4, Cytotoxic T-lymphocyte protein 4 , Cytotoxic T-lymphocyte-associated antigen 4, CH29-120A16.2-001, Cytotoxic T-lymphocyte protein 4 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Mouse Ctla4(37-162 aa) |
| Molecular Name | Ctla4 |
| Product Introduction | 细胞毒性T淋巴细胞蛋白4参与免疫反应并调节T淋巴细胞的活化。。 |
| Molecular Weight | 55 kDa |
| Expression System | HEK293F Cells |
| Species | Mouse |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| Purification | Affinity Purification |
| Uniprot ID | Q6GTR6 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. {ECO:0000256|ARBA:ARBA00002230}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its ability to inhibit IL-2 secretion by stimulated Jurkat human acute T cell leukemia cells. The ED50 forthis effect is 0.1-0.4 µg/mL when stimulated with 1 µg/mL Recombinant Human B7‑1/CD80 Fc Chimera in the presence of PHA. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
销售微信
官方公众号
0
