| Alias | 跨膜蛋白PVRIG, Transmembrane protein PVRIG , CD112 receptor, CD112R, Poliovirus receptor-related immunoglobulin domain-containing protein, C7orf15, Transmembrane protein PVRIG |
| Catalog Number | KRP472 |
| Molecular Name | PVRIG |
| Molecular Weight | 51-57 kDa |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥90% |
| Product Description | Human PVRIG(Thr41-Leu172&Glu43-Leu172) |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | < 0.1 EU per ug |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding. {ECO:0000269|PubMed:26755705}. |
| Species | Human |
| Purification | Affinity Purification |
| Endotoxin | Supplied in PBS |
| Biological Activity | Measured by its binding ability in a functional ELISA. When Recombinant Human PVRIG Fc Chimera is immobilized at 1 μg/mL, 100 μL/well, the concentration of Recombinant Human Nectin- 2/CD112 that produces 50% of the optimal binding response is 0.4- 2.4 μg/ |
| Uniprot ID | Q6DKI7 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Display Peptides | HEK293F Cells |
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