KRP470
白细胞介素11受体亚单位alpha-1, Interleukin-11 receptor subunit alpha-1 , IL-11 receptor subunit alpha-1, IL-11R subunit alpha-1, IL-11R-alpha-1, IL-11RA1, Enhancer trap locus homolog 2, Etl-2, Novel cytokine receptor 1, NR-1, NR1, [Cleaved into: Soluble interleukin
| Catalog Number | KRP470 |
| Alias | 白细胞介素11受体亚单位alpha-1, Interleukin-11 receptor subunit alpha-1 , IL-11 receptor subunit alpha-1, IL-11R subunit alpha-1, IL-11R-alpha-1, IL-11RA1, Enhancer trap locus homolog 2, Etl-2, Novel cytokine receptor 1, NR-1, NR1, [Cleaved into: Soluble interleukin |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Mouse Il11ra1(1-367 aa) |
| Molecular Name | Il11ra1 |
| Product Introduction | 白细胞介素11受体亚单位alpha-1通过影响细胞增殖和分化，调节免疫反应。。 |
| Molecular Weight | 47 kDa |
| Expression System | HEK293F Cells |
| Species | Mouse |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥90% |
| Purification | Affinity Purification |
| Uniprot ID | Q64385 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth.; [Soluble interleukin-11 receptor subunit alpha]: Soluble form of IL11 receptor (sIL11RA) that acts as an agonist of IL11 activity. The IL11:sIL11RA complex binds to IL6ST/gp130 on cell surfaces and induces signaling also on cells that do not express membrane-bound IL11RA in a process called IL11 trans-signaling. {ECO:0000250|UniProtKB:Q14626}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured in a cell proliferation assay using T11 mouse plasmacytoma cells. The ED50 forthis effect is 0.5-2 µg/mL in the presence of 0.75 ng/mL Recombinant Mouse IL‑11. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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