KRP462
受体酪氨酸激酶erbB-3, Receptor tyrosine-protein kinase erbB-3 , EC 2.7.10.1, Glial growth factor receptor, Proto-oncogene-like protein c-ErbB-3, Receptor tyrosine-protein kinase erbB-3
| Catalog Number | KRP462 |
| Alias | 受体酪氨酸激酶erbB-3, Receptor tyrosine-protein kinase erbB-3 , EC 2.7.10.1, Glial growth factor receptor, Proto-oncogene-like protein c-ErbB-3, Receptor tyrosine-protein kinase erbB-3 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Mouse Erbb3(20-641 aa) |
| Molecular Name | Erbb3 |
| Product Introduction | 受体酪氨酸激酶erbB-3参与免疫细胞的增殖与分化，调节免疫反应。。 |
| Molecular Weight | 120-135 kDa |
| Expression System | HEK293F Cells |
| Species | Mouse |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥90% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | Q61526 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation. {ECO:0000250|UniProtKB:P21860}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its ability to bind Recombinant Human NRG1‑ beta 1/HRG1‑ beta 1 Extracellular Domain in a functional ELISA with an estimated KD <15 nM. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
销售微信
官方公众号
0
