KRP460
壳聚糖酶3类似蛋白1, Chitinase-3-like protein 1 , BRP39 protein, Breast regression protein 39, Cartilage glycoprotein 39, CGP-39, GP-39, Brp39, Chil1, Chitinase-3-like protein 1
| Alias | 壳聚糖酶3类似蛋白1, Chitinase-3-like protein 1 , BRP39 protein, Breast regression protein 39, Cartilage glycoprotein 39, CGP-39, GP-39, Brp39, Chil1, Chitinase-3-like protein 1 |
| Catalog Number | KRP460 |
| Molecular Name | Chi3l1 |
| Molecular Weight | 41 kDa |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Product Description | Mouse Chi3l1(22-381 aa) |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | < 0.1 EU per ug |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung. {ECO:0000269|PubMed:16472595, ECO:0000269|PubMed:19041398, ECO:0000269|PubMed:19414556, ECO:0000269|PubMed:20558631, ECO:0000269|PubMed:21546314, ECO:0000269|PubMed:22817986}. |
| Species | Mouse |
| Purification | Affinity Purification |
| Endotoxin | Supplied in PBS |
| Biological Activity | Measured by the ability of the immobilized protein to support the adhesion of FaDu human squamous cell carcinoma cells. When 5 x 10^4 cells per well are added to rmCHI3- L1 coated plate, cell adhesion is enhanced in a dose dependent manner after 30 minute |
| Uniprot ID | Q61362 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Display Peptides | HEK293F Cells |
销售微信
官方公众号
0
