Recombinant Mouse Reelin Protein, C-His Tag
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产品编号
KRP458
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别名
Reelin, Reelin , EC 3.4.21.-, Reeler protein, Rl, Reelin
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KRP458 |
| Alias | Reelin, Reelin , EC 3.4.21.-, Reeler protein, Rl, Reelin |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Mouse Reln(Leu1221-Ile2661) |
| Molecular Name | Reln |
| Product Introduction | Reelin参与关节和软骨修复，调节细胞增殖与迁移。。 |
| Molecular Weight | 145-160 kDa |
| Expression System | HEK293F Cells |
| Species | Mouse |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥90% |
| Purification | Affinity Purification |
| Uniprot ID | Q60841-1 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Extracellular matrix serine protease secreted by pioneer neurons that plays a role in layering of neurons in the cerebral cortex and cerebellum by coordinating cell positioning during neurodevelopment (PubMed:10880573, PubMed:11689558, PubMed:7715726, PubMed:8987733). Regulates microtubule function in neurons and neuronal migration (PubMed:10880573, PubMed:7715726, PubMed:8987733). Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (PubMed:10571241). Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration (PubMed:11689558, PubMed:7715726, PubMed:8987733). Enzymatic activity is important for the modulation of cell adhesion (PubMed:11689558, PubMed:8987733). {ECO:0000269|PubMed:10571241, ECO:0000269|PubMed:10880573, ECO:0000269|PubMed:11689558, ECO:0000269|PubMed:7715726, ECO:0000269|PubMed:8987733}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its ability to bind biotinylated rhApoE R2 in a functional ELISA. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
FAQ
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表达后的蛋白需要进行质控检测吗？
是的，质量控制检测（如纯度、浓度、功能活性、稳定性等）是确保蛋白质量的关键步骤。
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