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Recombinant Mouse Reelin Protein, C-His Tag

Recombinant Mouse Reelin Protein, C-His Tag

产品编号

KRP458

别名

Reelin, Reelin , EC 3.4.21.-, Reeler protein, Rl, Reelin

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
AliasReelin, Reelin , EC 3.4.21.-, Reeler protein, Rl, Reelin
Catalog NumberKRP458
Molecular NameReln
Molecular Weight145-160 kDa
Size20ug, 50ug, 100ug, 200ug, 1mg
Concentration联系销售经理获得最新批次的浓度
Purity≥90%
Product DescriptionMouse Reln(Leu1221-Ile2661)
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation< 0.1 EU per ug
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundExtracellular matrix serine protease secreted by pioneer neurons that plays a role in layering of neurons in the cerebral cortex and cerebellum by coordinating cell positioning during neurodevelopment (PubMed:10880573, PubMed:11689558, PubMed:7715726, PubMed:8987733). Regulates microtubule function in neurons and neuronal migration (PubMed:10880573, PubMed:7715726, PubMed:8987733). Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (PubMed:10571241). Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration (PubMed:11689558, PubMed:7715726, PubMed:8987733). Enzymatic activity is important for the modulation of cell adhesion (PubMed:11689558, PubMed:8987733). {ECO:0000269|PubMed:10571241, ECO:0000269|PubMed:10880573, ECO:0000269|PubMed:11689558, ECO:0000269|PubMed:7715726, ECO:0000269|PubMed:8987733}.
SpeciesMouse
PurificationAffinity Purification
EndotoxinSupplied in PBS
Biological ActivityMeasured by its ability to bind biotinylated rhApoE R2 in a functional ELISA.
Uniprot IDQ60841-1
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。
Display PeptidesHEK293F Cells
FAQ
  • 问:表达后的蛋白需要进行质控检测吗? 答: 是的,质量控制检测(如纯度、浓度、功能活性、稳定性等)是确保蛋白质量的关键步骤。

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