Recombinant Human MICB Protein, C-His Tag
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产品编号
KRP442
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别名
MHC I类多肽相关序列B, MHC class I polypeptide-related sequence B , MIC-B, PERB11.2, MHC class I polypeptide-related sequence B
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Alias | MHC I类多肽相关序列B, MHC class I polypeptide-related sequence B , MIC-B, PERB11.2, MHC class I polypeptide-related sequence B |
| Catalog Number | KRP442 |
| Molecular Name | MICB |
| Molecular Weight | 50-55 kDa |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Product Description | Human MICB(23-308 aa) |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | < 0.1 EU per ug |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Widely expressed membrane-bound protein which acts as a ligand to stimulate an activating receptor KLRK1/NKG2D, expressed on the surface of essentially all human natural killer (NK), gammadelta T and CD8+ alphabeta T-cells (PubMed:11491531, PubMed:11777960). Up-regulated in stressed conditions, such as viral and bacterial infections or DNA damage response, serves as signal of cellular stress, and engagement of KLRK1/NKG2D by MICA triggers NK-cells resulting in a range of immune effector functions, such as cytotoxicity and cytokine production. {ECO:0000269|PubMed:11491531, ECO:0000269|PubMed:11777960, ECO:0000269|PubMed:9497295}. |
| Species | Human |
| Purification | Affinity Purification |
| Endotoxin | Supplied in PBS |
| Biological Activity | Measured by its binding ability in a functional ELISA. When Recombinant Human NKG2D/CD314 Fc Chimera is immobilized at 0.125 μg/mL, 100 μL/well, the concentration of Recombinant Human MICB Histag that produces 50% of the optimal binding response is approx |
| Uniprot ID | Q29980-1 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Display Peptides | HEK293F Cells |
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