Recombinant Human MICB Protein, C-His Tag_天津卡梅德科技发展有限公司

Recombinant Human MICB Protein, C-His Tag

产品编号

KRP442

别名

MHC I类多肽相关序列B, MHC class I polypeptide-related sequence B , MIC-B, PERB11.2, MHC class I polypeptide-related sequence B

规格

20ug
50ug
100ug
200ug
1mg

DATASHEET MSDS

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产品介绍

Catalog Number	KRP442
Alias	MHC I类多肽相关序列B, MHC class I polypeptide-related sequence B , MIC-B, PERB11.2, MHC class I polypeptide-related sequence B
Size	20ug, 50ug, 100ug, 200ug, 1mg
Product Description	Human MICB(23-308 aa)
Molecular Name	MICB
Product Introduction	MHC I类多肽相关序列B通过调节免疫系统和神经细胞的信号传递，促进细胞生长。。
Molecular Weight	50-55 kDa
Expression System	HEK293F Cells
Species	Human
Concentration	联系销售经理获得最新批次的浓度
Purity	≥95%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	Q29980-1
Storage Condition	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation	Supplied in PBS
Shipping Condition	This product is shipped on ice packs or dry ice.
Background	Widely expressed membrane-bound protein which acts as a ligand to stimulate an activating receptor KLRK1/NKG2D, expressed on the surface of essentially all human natural killer (NK), gammadelta T and CD8+ alphabeta T-cells (PubMed:11491531, PubMed:11777960). Up-regulated in stressed conditions, such as viral and bacterial infections or DNA damage response, serves as signal of cellular stress, and engagement of KLRK1/NKG2D by MICA triggers NK-cells resulting in a range of immune effector functions, such as cytotoxicity and cytokine production. {ECO:0000269\|PubMed:11491531, ECO:0000269\|PubMed:11777960, ECO:0000269\|PubMed:9497295}.
Endotoxin	< 0.1 EU per ug
Biological Activity	Measured by its binding ability in a functional ELISA. When Recombinant Human NKG2D/CD314 Fc Chimera is immobilized at 0.125 μg/mL, 100 μL/well, the concentration of Recombinant Human MICB Histag that produces 50% of the optimal binding response is approx
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。