| Catalog Number | KRP398 |
| Alias | 多肽N-乙酰半乳糖氨基转移酶2, Polypeptide N-acetylgalactosaminyltransferase 2 , EC 2.4.1.41, Polypeptide GalNAc transferase 2, GalNAc-T2, pp-GaNTase 2, Protein-UDP acetylgalactosaminyltransferase 2, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2, [Cleaved |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Human GALNT2(52-571 aa) |
| Molecular Name | GALNT2 |
| Product Introduction | 多肽N-乙酰半乳糖氨基转移酶2通过影响糖基转移反应,调节细胞功能。。 |
| Molecular Weight | 55-65 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥90% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | Q10471 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region. Involved in O-linked glycosylation of APOC-III, ANGPTL3 and PLTP. It participates in the regulation of HDL-C metabolism (PubMed:27508872, PubMed:32293671). {ECO:0000269|PubMed:12438318, ECO:0000269|PubMed:16207894, ECO:0000269|PubMed:16434399, ECO:0000269|PubMed:25939779, ECO:0000269|PubMed:27508872, ECO:0000269|PubMed:32293671, ECO:0000269|PubMed:7592619, ECO:0000269|PubMed:9295285}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its ability to transfer GalNAc from UDP-GalNAc to peptide EA2. The specific activity is >350 pmol/min/μg, as measured under the described conditions. |
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |