KRP396
纤维蛋白原样蛋白1, Fibrinogen-like protein 1 , HP-041, Hepassocin, HPS, Hepatocyte-derived fibrinogen-related protein 1, HFREP-1, Liver fibrinogen-related protein 1, LFIRE-1, HFREP1, Fibrinogen-like protein 1
| Catalog Number | KRP396 |
| Alias | 纤维蛋白原样蛋白1, Fibrinogen-like protein 1 , HP-041, Hepassocin, HPS, Hepatocyte-derived fibrinogen-related protein 1, HFREP-1, Liver fibrinogen-related protein 1, LFIRE-1, HFREP1, Fibrinogen-like protein 1 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Human FGL1(23-312 aa) |
| Molecular Name | FGL1 |
| Product Introduction | 纤维蛋白原样蛋白1调节血液凝固过程，支持免疫反应与修复过程。。 |
| Molecular Weight | 60-65 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥92% |
| SDS-PAGE | |
| Purification | Affinity Purification |
| Uniprot ID | Q08830 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3 (PubMed:30580966). Responsible for LAG3 T-cell inhibitory function (PubMed:30580966). Binds LAG3 independently from MHC class II (MHC-II) (PubMed:30580966). Secreted by, and promotes growth of, hepatocytes (PubMed:11470158, PubMed:19880967). {ECO:0000269|PubMed:11470158, ECO:0000269|PubMed:19880967, ECO:0000269|PubMed:30580966}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Immobilized recombinant Human FGL1 at 5 μg/mL (100 μL/well) can bind recombinant Human LAG3 with a linearrange of 0.5-21.6 ng/mL. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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