| Alias | 分泌Frizzled相关蛋白3, Secreted frizzled-related protein 3 , sFRP-3, Frezzled, Fritz, Frizzled-related protein 1, FrzB-1, Fiz, Fre, Frzb1, Sfrp3, Secreted frizzled-related protein 3 |
| Catalog Number | KRP363 |
| Molecular Name | Frzb |
| Molecular Weight | 37 kDa |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Product Description | Mouse Frzb(33-323 aa) |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | < 0.1 EU per ug |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development (By similarity). {ECO:0000250, ECO:0000269|PubMed:9178261}. |
| Species | Mouse |
| Purification | Affinity Purification |
| Endotoxin | Supplied in PBS |
| Biological Activity | Measured by its ability to inhibit proliferation in MC3T3‑E1 mouse preosteoblast cells. The ED50 forthis effect is 1.5‑6.0 µg/mL. |
| Uniprot ID | P97401 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Display Peptides | HEK293F Cells |
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