| Catalog Number | KRP361 |
| Alias | 分泌Frizzled相关蛋白2, Secreted frizzled-related protein 2 , sFRP-2, Protein SDF5, Secreted apoptosis-related protein 1, SARP-1, Sarp1, Sdf5, Secreted frizzled-related protein 2 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Mouse Sfrp2(Leu25-Cys295) |
| Molecular Name | Sfrp2 |
| Product Introduction | 分泌Frizzled相关蛋白2通过调节分泌型Frizzled蛋白,影响细胞间的信号传递。。 |
| Molecular Weight | 35-40 kDa |
| Expression System | HEK293F Cells |
| Species | Mouse |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| Purification | Affinity Purification |
| Uniprot ID | P97299 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its ability to compete with Frizzled-1 for binding to biotinylated Wnt-3a. The IC50 value is 0.7-3.5 nM, under conditions in which Recombinant Mouse (rm) Frizzled‑1 Fc Chimera is present at 2.1 nM, and biotinylated rmWnt-3a concentration is 2. |
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |