Recombinant Rat IFN-beta Protein, C-His Tag_天津卡梅德科技发展有限公司

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Recombinant Rat IFN-beta Protein, C-His Tag

Recombinant Rat IFN-beta Protein, C-His Tag

产品编号

KRP354

别名

干扰素β（IFN-β）, Interferon beta , IFN-beta, Ifnb, Interferon beta

规格

20ug
50ug
100ug
200ug
1mg

DATASHEET MSDS

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产品介绍

Alias	干扰素β（IFN-β）, Interferon beta , IFN-beta, Ifnb, Interferon beta
Catalog Number	KRP354
Molecular Name	Ifnb1
Molecular Weight	30-38 kDa
Size	20ug, 50ug, 100ug, 200ug, 1mg
Concentration	联系销售经理获得最新批次的浓度
Purity	≥95%
Product Description	Rat Ifnb1(22-184 aa)
Storage Condition	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation	< 0.1 EU per ug
Shipping Condition	This product is shipped on ice packs or dry ice.
Background	Type I interferon cytokine that plays a key role in the innate immune response to infection, developing tumors and other inflammatory stimuli. Signals via binding to high-affinity (IFNAR2) and low-affinity (IFNAR1) heterodimeric receptor, activating the canonical Jak-STAT signaling pathway resulting in transcriptional activation or repression of interferon-regulated genes that encode the effectors of the interferon response, such as antiviral proteins, regulators of cell proliferation and differentiation, and immunoregulatory proteins (By similarity). Signals mostly via binding to a IFNAR1-IFNAR2 heterodimeric receptor, but can also function with IFNAR1 alone and independently of Jak-STAT pathways. Elicits a wide variety of responses, including antiviral and antibacterial activities, and can regulate the development of B-cells, myelopoiesis and lipopolysaccharide (LPS)-inducible production of tumor necrosis factor. Plays a role in neuronal homeostasis by regulating dopamine turnover and protecting dopaminergic neurons: acts by promoting neuronal autophagy and alpha-synuclein clearance, thereby preventing dopaminergic neuron loss. IFNB1 is more potent than interferon-alpha (IFN-alpha) in inducing the apoptotic and antiproliferative pathways required for control of tumor cell growth (By similarity). {ECO:0000250\|UniProtKB:P01574, ECO:0000250\|UniProtKB:P01575}.
Species	Rat
Purification	Affinity Purification
Endotoxin	Supplied in PBS
Biological Activity	Interferon was titrated with the use of the cytopathic effect inhibition assay. In this antiviral assay forinterferon, about 1 unit/ml of interferon is the quantity necessary to produce a cytopathic effect of 50%. As there is no international Rat IFN-beta
Uniprot ID	P70499
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。
Display Peptides	HEK293F Cells

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