KRP311
白细胞介素-12受体亚单位beta-1, Interleukin-12 receptor subunit beta-1 , IL-12 receptor subunit beta-1, IL-12R subunit beta-1, IL-12R-beta-1, IL-12RB1, IL-12 receptor beta component, CD antigen CD212, IL12R, IL12RB, Interleukin-12 receptor subunit beta-1, IL-12 rece
| Catalog Number | KRP311 |
| Alias | 白细胞介素-12受体亚单位beta-1, Interleukin-12 receptor subunit beta-1 , IL-12 receptor subunit beta-1, IL-12R subunit beta-1, IL-12R-beta-1, IL-12RB1, IL-12 receptor beta component, CD antigen CD212, IL12R, IL12RB, Interleukin-12 receptor subunit beta-1, IL-12 rece |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Human IL12RB1(24-540 aa) |
| Molecular Name | IL12RB1 |
| Product Introduction | 白细胞介素-12受体亚单位beta-1调节免疫细胞增殖和分化的受体。。 |
| Molecular Weight | 110 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| Purification | Affinity Purification |
| Uniprot ID | P42701-1 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Also associates with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade. {ECO:0000269|PubMed:12023369}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its binding ability in a functional ELISA. Recombinant Human IL‑12 R beta 1 Fc Chimera binds to Recombinant Human IL‑12 with an ED50 of 3.00-30.0 ng/mL |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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