Alias | 白细胞介素-12受体亚单位beta-1, Interleukin-12 receptor subunit beta-1 , IL-12 receptor subunit beta-1, IL-12R subunit beta-1, IL-12R-beta-1, IL-12RB1, IL-12 receptor beta component, CD antigen CD212, IL12R, IL12RB, Interleukin-12 receptor subunit beta-1, IL-12 rece |
Catalog Number | KRP311 |
Molecular Name | IL12RB1 |
Molecular Weight | 110 kDa |
Size | 20ug, 50ug, 100ug, 200ug, 1mg |
Concentration | 联系销售经理获得最新批次的浓度 |
Purity | ≥95% |
Product Description | Human IL12RB1(24-540 aa) |
Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
Formulation | < 0.1 EU per ug |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Background | Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Also associates with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade. {ECO:0000269|PubMed:12023369}. |
Species | Human |
Purification | Affinity Purification |
Endotoxin | Supplied in PBS |
Biological Activity | Measured by its binding ability in a functional ELISA. Recombinant Human IL‑12 R beta 1 Fc Chimera binds to Recombinant Human IL‑12 with an ED50 of 3.00-30.0 ng/mL |
Uniprot ID | P42701-1 |
Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |
Display Peptides | HEK293F Cells |