| Catalog Number | KRP307 |
| Alias | 基质金属蛋白酶9, Matrix metalloproteinase-9 , MMP-9, EC 3.4.24.35, 92 kDa gelatinase, 92 kDa type IV collagenase, Gelatinase B, GELB, Clg4b, Matrix metalloproteinase-9, 92 kDa gelatinase, |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Mouse Mmp9(Ala20-Pro730) |
| Molecular Name | Mmp9 |
| Product Introduction | 基质金属蛋白酶9参与基质降解过程,调节细胞外基质的重塑。。 |
| Molecular Weight | 100-110 kDa |
| Expression System | HEK293F Cells |
| Species | Mouse |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | P41245 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration (By similarity). Could play a role in bone osteoclastic resorption (PubMed:8132709). Cleaves KiSS1 at a Gly-|-Leu bond (By similarity). Cleaves NINJ1 to generate the Secreted ninjurin-1 form (PubMed:23142597, PubMed:32883094). Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide (By similarity). {ECO:0000250|UniProtKB:P14780, ECO:0000269|PubMed:23142597, ECO:0000269|PubMed:32883094, ECO:0000269|PubMed:8132709}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its ability to cleave the fluorogenic peptide substrate Mca-PLGL-Dpa-AR-NH2. The specific activity is >1900 pmol/min/μg. |
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |