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Recombinant Human GC-C Protein, C-His Tag

Recombinant Human GC-C Protein, C-His Tag

产品编号

KRP247

别名

GC-C, Guanylyl cyclase C, GC-C, EC:4.6.1.2, Heat-stable enterotoxin receptor, STA receptor, hSTAR, Intestinal guanylate cyclase

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
AliasGC-C, Guanylyl cyclase C, GC-C, EC:4.6.1.2, Heat-stable enterotoxin receptor, STA receptor, hSTAR, Intestinal guanylate cyclase
Catalog NumberKRP247
Molecular NameGC-C
Molecular Weight60-90 kDa
Size20ug, 50ug, 100ug, 200ug, 1mg
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
SDS-PAGE
Product DescriptionHuman GC-C(24-430 aa)
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation< 0.1 EU per ug
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundGuanylyl cyclase that catalyzes synthesis of cyclic GMP (cGMP) from GTP (PubMed:11950846, PubMed:1718270, PubMed:22436048, PubMed:22521417, PubMed:23269669). Receptor for the E.coli heat-stable enterotoxin; E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GUCY2C (PubMed:1680854, PubMed:1718270). Also activated by the endogenous peptides guanylin and uroguanylin (PubMed:8381596).
SpeciesHuman
PurificationAffinity Purification
EndotoxinSupplied in PBS
Biological ActivityImmobilized Human GUCY2C at 1 μg/mL (100 μL/well) can bind GUCY2C antibody with a linear range of 1- 144 ng/mL.
Uniprot IDP25092-1
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。
Display PeptidesHEK293F Cells

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