Alias | GC-C, Guanylyl cyclase C, GC-C, EC:4.6.1.2, Heat-stable enterotoxin receptor, STA receptor, hSTAR, Intestinal guanylate cyclase |
Catalog Number | KRP247 |
Molecular Name | GC-C |
Molecular Weight | 60-90 kDa |
Size | 20ug, 50ug, 100ug, 200ug, 1mg |
Concentration | 联系销售经理获得最新批次的浓度 |
Purity | ≥95% |
SDS-PAGE |  |
Product Description | Human GC-C(24-430 aa) |
Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
Formulation | < 0.1 EU per ug |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Background | Guanylyl cyclase that catalyzes synthesis of cyclic GMP (cGMP) from GTP (PubMed:11950846, PubMed:1718270, PubMed:22436048, PubMed:22521417, PubMed:23269669).
Receptor for the E.coli heat-stable enterotoxin; E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GUCY2C (PubMed:1680854, PubMed:1718270).
Also activated by the endogenous peptides guanylin and uroguanylin (PubMed:8381596). |
Species | Human |
Purification | Affinity Purification |
Endotoxin | Supplied in PBS |
Biological Activity | Immobilized Human GUCY2C at 1 μg/mL (100 μL/well) can bind GUCY2C antibody with a linear range of 1- 144 ng/mL. |
Uniprot ID | P25092-1 |
Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |
Display Peptides | HEK293F Cells |