Recombinant Human GC-C Protein, C-His Tag_天津卡梅德科技发展有限公司

KRP247

GC-C, Guanylyl cyclase C, GC-C, EC:4.6.1.2, Heat-stable enterotoxin receptor, STA receptor, hSTAR, Intestinal guanylate cyclase

DATASHEET MSDS

产品介绍

Catalog Number	KRP247
Alias	GC-C, Guanylyl cyclase C, GC-C, EC:4.6.1.2, Heat-stable enterotoxin receptor, STA receptor, hSTAR, Intestinal guanylate cyclase
Size	20ug, 50ug, 100ug, 200ug, 1mg
Product Description	Human GC-C(24-430 aa)
Molecular Name	GC-C
Product Introduction	参与肠道中水和电解质的平衡，调节肠道功能。
Molecular Weight	60-90 kDa
Expression System	HEK293F Cells
Species	Human
Concentration	联系销售经理获得最新批次的浓度
Purity	≥95%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	P25092-1
Storage Condition	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation	Supplied in PBS
Shipping Condition	This product is shipped on ice packs or dry ice.
Background	Guanylyl cyclase that catalyzes synthesis of cyclic GMP (cGMP) from GTP (PubMed:11950846, PubMed:1718270, PubMed:22436048, PubMed:22521417, PubMed:23269669). Receptor for the E.coli heat-stable enterotoxin; E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GUCY2C (PubMed:1680854, PubMed:1718270). Also activated by the endogenous peptides guanylin and uroguanylin (PubMed:8381596).
Endotoxin	< 0.1 EU per ug
Biological Activity	Immobilized Human GUCY2C at 1 μg/mL (100 μL/well) can bind GUCY2C antibody with a linear range of 1- 144 ng/mL.
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。