| Alias | 类胰岛素生长因子结合蛋白6, Insulin-like growth factor-binding protein 6 , IBP-6, IGF-binding protein 6, IGFBP-6, IBP6, Insulin-like growth factor-binding protein 6, IGF-binding protein 6, |
| Catalog Number | KRP245 |
| Molecular Name | IGFBP6 |
| Molecular Weight | 36 kDa |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥97% |
| SDS-PAGE |  |
| Product Description | Human IGFBP6(25-240 aa) |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | < 0.1 EU per ug |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Activates the MAPK signaling pathway and induces cell migration (PubMed:24003225). {ECO:0000269|PubMed:24003225}. |
| Species | Human |
| Purification | Affinity Purification |
| Endotoxin | Supplied in PBS |
| Biological Activity | Measured by its ability to inhibit the biological activity of IGF-I orIGF-II on MCF‑7 human breast cancer cells. The ED50 forthis effect is 0.025- 0.15 µg/mL in the presence of 14 ng/mL Recombinant Human IGF‑II. |
| Uniprot ID | P24592 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Display Peptides | HEK293F Cells |
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