KRP233
整合素结合糖蛋白, Integrin-binding sialoprotein , Bone sialoprotein 2, Bone sialoprotein II, BSP II, Cell-binding sialoprotein, BNSP, Integrin-binding sialoprotein, Bone sialoprotein 2,
| Catalog Number | KRP233 |
| Alias | 整合素结合糖蛋白, Integrin-binding sialoprotein , Bone sialoprotein 2, Bone sialoprotein II, BSP II, Cell-binding sialoprotein, BNSP, Integrin-binding sialoprotein, Bone sialoprotein 2, |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Human IBSP(17-317 aa) |
| Molecular Name | IBSP |
| Product Introduction | 整合素结合糖蛋白参与骨骼细胞结合与细胞外基质的修复。。 |
| Molecular Weight | 75-90 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥90% |
| SDS-PAGE | |
| Purification | Affinity Purification |
| Uniprot ID | P21815 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Binds tightly to hydroxyapatite (PubMed:11459848). Appears to form an integral part of the mineralized matrix (PubMed:1818768). Probably important to cell-matrix interaction (PubMed:1818768). Promotes adhesion and migration of various cells via the alpha-V/beta-3 integrin receptor (ITGAV:ITGB3) (PubMed:10640428, PubMed:11459848, PubMed:24103036). {ECO:0000269|PubMed:10640428, ECO:0000269|PubMed:11459848, ECO:0000269|PubMed:1818768, ECO:0000269|PubMed:24103036}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by the ability of the immobilized protein to support the adhesion of the MCF‑7 human breast cancer cells. The ED50 of this effect is 0.06- 0.6 μg/mL. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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