Alias | 颗粒酶H, Granzyme H , EC 3.4.21.-, CCP-X, Cathepsin G-like 2, CTSGL2, Cytotoxic T-lymphocyte proteinase, Cytotoxic serine protease C, CSP-C, CGL2, CTSGL2, Granzyme H, Cathepsin G-like 2, |
Catalog Number | KRP222 |
Molecular Name | GZMH |
Molecular Weight | 38-40 kDa |
Size | 20ug, 50ug, 100ug, 200ug, 1mg |
Concentration | 联系销售经理获得最新批次的浓度 |
Purity | ≥95% |
SDS-PAGE |  |
Product Description | Human GZMH(19-246 aa) |
Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
Formulation | < 0.1 EU per ug |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Background | Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication. {ECO:0000269|PubMed:22156497, ECO:0000269|PubMed:23269243}. |
Species | Human |
Purification | Affinity Purification |
Endotoxin | Supplied in PBS |
Biological Activity | Measured by its ability to cleave a peptide substrate, Succinyl-Phe-Leu-Phe-ThioBenzyl ester(Suc-FLFSBzl), in the presence of 5,5’- Dithio-bis (2- nitrobenzoic acid) (DTNB). The specific activity is >5,000 pmol/min/µg, as measured under the described cond |
Uniprot ID | P20718 |
Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |
Display Peptides | HEK293F Cells |