Recombinant Human EPO-R Protein, C-hFc and His tag_天津卡梅德科技发展有限公司

Recombinant Human EPO-R Protein, C-hFc and His tag

产品编号

KRP213

别名

红细胞生成素受体, Erythropoietin receptor , EPO-R, Erythropoietin receptor, EPO-R,

规格

20ug
50ug
100ug
200ug
1mg

DATASHEET MSDS

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产品介绍

Catalog Number	KRP213
Alias	红细胞生成素受体, Erythropoietin receptor , EPO-R, Erythropoietin receptor, EPO-R,
Size	20ug, 50ug, 100ug, 200ug, 1mg
Product Description	Human EPOR(25-250 aa)
Molecular Name	EPOR
Product Introduction	红细胞生成素受体红细胞生成素受体，调节红细胞生成。。
Molecular Weight	55-60 kDa
Expression System	HEK293F Cells
Species	Human
Concentration	联系销售经理获得最新批次的浓度
Purity	≥95%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	P19235
Storage Condition	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation	Supplied in PBS
Shipping Condition	This product is shipped on ice packs or dry ice.
Background	Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation (PubMed:10388848, PubMed:2163695, PubMed:2163696, PubMed:8662939, PubMed:9774108). Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade (By similarity). In some cell types, can also activate STAT1 and STAT3 (PubMed:11756159). May also activate the LYN tyrosine kinase (By similarity). {ECO:0000250\|UniProtKB:P14753, ECO:0000269\|PubMed:10388848, ECO:0000269\|PubMed:11756159, ECO:0000269\|PubMed:2163695, ECO:0000269\|PubMed:2163696, ECO:0000269\|PubMed:8662939, ECO:0000269\|PubMed:9774108}.; [Isoform EPOR-T]: Acts as a dominant-negative receptor of EPOR-mediated signaling. {ECO:0000269\|PubMed:1324524}.
Endotoxin	< 0.1 EU per ug
Biological Activity	Immobilized Human EPO Protein at 2μg/mL (100 μL/well) can bind EPOR with a linearrange of 0.24-12.02 ng/mL.
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。