| Catalog Number | KRP204 |
| Alias | 血管内皮生长因子A, Vascular endothelial growth factor A , VEGF-A, Vascular permeability factor, VPF, Vegf, Vascular endothelial growth factor A, VEGF-A, |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Rat Vegfa(Ala27-Arg190(isoform2)) |
| Molecular Name | Vegfa |
| Product Introduction | 血管内皮生长因子A促进血管生长，调节血管通透性。。 |
| Molecular Weight | 25 kDa |
| Expression System | HEK293F Cells |
| Species | Rat |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | P16612-2 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. May play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity). Also binds the DEAR/FBXW7-AS1 receptor (By similarity). {ECO:0000250|UniProtKB:P15692, ECO:0000250|UniProtKB:Q00731, ECO:0000269|PubMed:10878616}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. The ED50 forthis effect is 0.75‑3.75 ng/mL |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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