Recombinant Human Growth hormonereceptor Protein, C-hFc and His tag

产品编号

KRP162

别名

生长激素受体, Growth hormone receptor , GH receptor, Somatotropin receptor, [Cleaved into: Growth hormone-binding protein , GH-binding protein, GHBP, Serum-binding protein, ],

规格

20ug
50ug
100ug
200ug
1mg

DATASHEET MSDS

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产品介绍

Catalog Number	KRP162
Alias	生长激素受体, Growth hormone receptor , GH receptor, Somatotropin receptor, [Cleaved into: Growth hormone-binding protein , GH-binding protein, GHBP, Serum-binding protein, ],
Size	20ug, 50ug, 100ug, 200ug, 1mg
Product Description	Human GHR(Ala 27-Tyr 264 )
Molecular Name	GHR
Product Introduction	生长激素受体生长激素受体，调节体内的生长和代谢功能。。
Molecular Weight	70-85 kDa
Expression System	HEK293F Cells
Species	Human
Concentration	联系销售经理获得最新批次的浓度
Purity	≥95%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	P10912
Storage Condition	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation	Supplied in PBS
Shipping Condition	This product is shipped on ice packs or dry ice.
Background	Receptor for pituitary gland growth hormone (GH1) involved in regulating postnatal body growth (PubMed:1549776, PubMed:2825030, PubMed:8943276). On ligand binding, couples to the JAK2/STAT5 pathway (PubMed:1549776, PubMed:15690087, PubMed:2825030, PubMed:8943276). {ECO:0000269\|PubMed:1549776, ECO:0000269\|PubMed:15690087, ECO:0000269\|PubMed:2825030, ECO:0000269\|PubMed:8943276}.; [Growth hormone-binding protein]: The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. {ECO:0000269\|PubMed:2825030}.; [Isoform 2]: Up-regulates the production of the soluble Growth hormone-binding protein form (GHBP) and acts as a negative inhibitor of growth hormone signaling. {ECO:0000269\|PubMed:8855247, ECO:0000269\|PubMed:9360546}.
Endotoxin	< 0.1 EU per ug
Biological Activity	Immobilized Human GH at 2 μg/mL (100 μL/well) can bind Human GHR with a linear range of 0.1-8.58 ng/mL；
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。