KRP162
生长激素受体, Growth hormone receptor , GH receptor, Somatotropin receptor, [Cleaved into: Growth hormone-binding protein , GH-binding protein, GHBP, Serum-binding protein, ],
| Alias | 生长激素受体, Growth hormone receptor , GH receptor, Somatotropin receptor, [Cleaved into: Growth hormone-binding protein , GH-binding protein, GHBP, Serum-binding protein, ], |
| Catalog Number | KRP162 |
| Molecular Name | GHR |
| Molecular Weight | 70-85 kDa |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Product Description | Human GHR(Ala 27-Tyr 264 ) |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | < 0.1 EU per ug |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Receptor for pituitary gland growth hormone (GH1) involved in regulating postnatal body growth (PubMed:1549776, PubMed:2825030, PubMed:8943276). On ligand binding, couples to the JAK2/STAT5 pathway (PubMed:1549776, PubMed:15690087, PubMed:2825030, PubMed:8943276). {ECO:0000269|PubMed:1549776, ECO:0000269|PubMed:15690087, ECO:0000269|PubMed:2825030, ECO:0000269|PubMed:8943276}.; [Growth hormone-binding protein]: The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. {ECO:0000269|PubMed:2825030}.; [Isoform 2]: Up-regulates the production of the soluble Growth hormone-binding protein form (GHBP) and acts as a negative inhibitor of growth hormone signaling. {ECO:0000269|PubMed:8855247, ECO:0000269|PubMed:9360546}. |
| Species | Human |
| Purification | Affinity Purification |
| Endotoxin | Supplied in PBS |
| Biological Activity | Immobilized Human GH at 2 μg/mL (100 μL/well) can bind Human GHR with a linear range of 0.1-8.58 ng/mL； |
| Uniprot ID | P10912 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Display Peptides | HEK293F Cells |
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