| Catalog Number | KRP062 |
| Alias | Follistatin相关蛋白3, Follistatin-related protein 3 , Follistatin-like protein 3, Follistatin-related gene protein, FLRG, UNQ674/PRO1308, |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Human FSTL3(27-263 aa) |
| Molecular Name | FSTL3 |
| Product Introduction | Follistatin相关蛋白3通过抑制血管生成，参与肿瘤进展的调控因子。。 |
| Molecular Weight | 38 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥90% |
| SDS-PAGE | |
| Purification | Affinity Purification |
| Uniprot ID | O95633 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family, such as activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiation. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 or the nuclear form is probably involved in transcriptional regulation via interaction with MLLT10. {ECO:0000269|PubMed:11948405, ECO:0000269|PubMed:15451575, ECO:0000269|PubMed:15574124, ECO:0000269|PubMed:16336961, ECO:0000269|PubMed:17868029, ECO:0000269|PubMed:17878677}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its ability to neutralize Activin mediated erythroid differentiation of K562 human chronic myelogenous leukemia cells. The ED50 forthis effect is 3-15 ng/mL in the presence of 7.5 ng/mL recombinant human Activin A. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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