| Catalog Number | KRP036 |
| Alias | Kunitz型蛋白酶抑制剂2, Kunitz-type protease inhibitor 2 , Hepatocyte growth factor activator inhibitor type 2, HAI-2, Placental bikunin, HAI2, KOP, |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Human SPINT2(1-197 aa) |
| Molecular Name | SPINT2 |
| Product Introduction | Kunitz型蛋白酶抑制剂2通过结合酪氨酸抑制细胞内的信号传导通路。 |
| Molecular Weight | 27 kDa & 32 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | O43291-1 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Inhibitor of HGFAC (PubMed:9346890). Also inhibits plasmin, and plasma and tissue kallikrein (PubMed:9115294). Inhibits serine protease activity of TMPRSS13 (PubMed:20977675, PubMed:28710277). Inhibits serine protease activity of ST14/matriptase and PRSS8/prostasin in vitro (PubMed:28710277, PubMed:30445423). {ECO:0000269|PubMed:20977675, ECO:0000269|PubMed:28710277, ECO:0000269|PubMed:30445423, ECO:0000269|PubMed:9115294, ECO:0000269|PubMed:9346890}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca RPKPVE-Nval WRK(Dnp)- NH2. The IC50 value is <4.6 nM, as measured underthe described conditions. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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