Alias | Kunitz型蛋白酶抑制剂2, Kunitz-type protease inhibitor 2 , Hepatocyte growth factor activator inhibitor type 2, HAI-2, Placental bikunin, HAI2, KOP, |
Catalog Number | KRP036 |
Molecular Name | SPINT2 |
Molecular Weight | 27 kDa & 32 kDa |
Size | 20ug, 50ug, 100ug, 200ug, 1mg |
Concentration | 联系销售经理获得最新批次的浓度 |
Purity | ≥95% |
SDS-PAGE |  |
Product Description | Human SPINT2(1-197 aa) |
Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
Formulation | < 0.1 EU per ug |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Background | Inhibitor of HGFAC (PubMed:9346890). Also inhibits plasmin, and plasma and tissue kallikrein (PubMed:9115294). Inhibits serine protease activity of TMPRSS13 (PubMed:20977675, PubMed:28710277). Inhibits serine protease activity of ST14/matriptase and PRSS8/prostasin in vitro (PubMed:28710277, PubMed:30445423). {ECO:0000269|PubMed:20977675, ECO:0000269|PubMed:28710277, ECO:0000269|PubMed:30445423, ECO:0000269|PubMed:9115294, ECO:0000269|PubMed:9346890}. |
Species | Human |
Purification | Affinity Purification |
Endotoxin | Supplied in PBS |
Biological Activity | Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca RPKPVE-Nval WRK(Dnp)- NH2. The IC50 value is <4.6 nM, as measured underthe described conditions. |
Uniprot ID | O43291-1 |
Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |
Display Peptides | HEK293F Cells |