| Alias | Kunitz型蛋白酶抑制剂1, Kunitz-type protease inhibitor 1 , Hepatocyte growth factor activator inhibitor type 1, HAI-1, HAI1, UNQ223/PRO256, |
| Catalog Number | KRP035 |
| Molecular Name | SPINT1 |
| Molecular Weight | 58 kDa |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Product Description | Human SPINT1(37-449 aa) |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | < 0.1 EU per ug |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Inhibitor of HGFAC (PubMed:9045658). Inhibits serine protease activity of ST14/matriptase in vitro (PubMed:28710277). Inhibits serine protease activity of TMPRSS13, via the BPTI/Kunitz inhibitor 1 domain (PubMed:20977675). {ECO:0000269|PubMed:20977675, ECO:0000269|PubMed:28710277, ECO:0000269|PubMed:9045658}. |
| Species | Human |
| Purification | Affinity Purification |
| Endotoxin | Supplied in PBS |
| Biological Activity | Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca- RPKPVE-Nval- WRK(Dnp)- NH2. The IC50 is <2 nM, as measured under the described conditions. |
| Uniprot ID | O43278-2 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Display Peptides | HEK293F Cells |
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