Recombinant Mouse Klotho Protein, C-His Tag
-
产品编号
KRP030
-
别名
克洛索蛋白, Klotho , EC 3.2.1.31,
-
规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Alias | 克洛索蛋白, Klotho , EC 3.2.1.31, |
| Catalog Number | KRP030 |
| Molecular Name | Kl |
| Molecular Weight | 125-130 kDa |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥90% |
| Product Description | Mouse Kl(Ala35-Lys982) |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | < 0.1 EU per ug |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1.; The Klotho peptide generated by cleavage of the membrane-bound isoform may be an anti-aging circulating hormone which would extend life span by inhibiting insulin/IGF1 signaling. |
| Species | Mouse |
| Purification | Affinity Purification |
| Endotoxin | Supplied in PBS |
| Biological Activity | Measured in a cell proliferation assay using BaF3 mouse pro‑B cells transfected with human FGF RIIIc. The ED50 forthis effect is 0.04- 0.4 µg/mL in the presence of 1 µg/mL of Recombinant Human FGF‑23 and 10 µg/mL of heparin. |
| Uniprot ID | O35082-1 |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Display Peptides | HEK293F Cells |
- 联系我们
- 电话：400-621-6806
- 手机：13116038708
- 邮箱：info@kmdbioscience.com
- 地址：天津市武清区国际企业社区A5栋
-
销售微信
-
官方公众号
-
400-621-6806 -
614353794 -
周一至周五 8:30-18:00 -
-
0
-
