| Catalog Number | KRP022 |
| Alias | 可卡因酯酶, Cocaine esterase , EC 3.1.1.84, Carboxylesterase 2, CE-2, hCE-2, EC 3.1.1.1, Methylumbelliferyl-acetate deacetylase 2, EC 3.1.1.56, ICE, |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Human CES2(27-559 aa) |
| Molecular Name | CES2 |
| Product Introduction | 可卡因酯酶参与细胞膜内外物质的转运过程。 |
| Molecular Weight | 63 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | O00748 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs (PubMed:9169443). Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine (PubMed:9169443). Hydrolyzes aspirin, substrates with large alcohol group and small acyl group and endogenous lipids such as triacylglycerol (PubMed:28677105). Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes of 2-arachidonoylglycerol and prostaglandins (PubMed:21049984). {ECO:0000269|PubMed:21049984, ECO:0000269|PubMed:9169443, ECO:0000303|PubMed:28677105}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its ability to hydrolyze p nitrophenylacetate. The specific activity is >30,000 pmol/min/μg, measured under the described conditions. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
取决于蛋白的稳定性和纯度。经过充分纯化的蛋白通常适用于X射线晶体学、NMR或冷冻电子显微镜等结构解析方法。
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