| Catalog Number | KRP013 |
| Alias | CD45, Receptor-type tyrosine-protein phosphatase C, EC:3.1.3.48, Leukocyte common antigen, L-CA, Lymphocyte antigen 5, Ly-5, T200, CD45 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Mouse CD45(Gln24-Lys564(NP_001104786.1)) |
| Molecular Name | CD45 |
| Product Introduction | CD45作为白细胞标志分子，参与调节T细胞、B细胞的激活和免疫反应。 |
| Molecular Weight | 140-160 kDa |
| Expression System | HEK293F Cells |
| Species | Mouse |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥90% |
| Purification | Affinity Purification |
| Uniprot ID | P06800 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its binding ability in a functional ELISA. When 0.5 μg/mL ofrmCD45 is captured onto a Mouse Anti polyHistidine Monoclonal Antibody coated plate, the concentration of rmGalectin-1 that produces 50% of the optimal binding is found to be approxim |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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