Recombinant Human Siglec-11 Protein, C-hFc and His tag_天津卡梅德科技发展有限公司

Recombinant Human Siglec-11 Protein, C-hFc and His tag

产品编号

KRP007

别名

唾液酸结合免疫球蛋白样凝集素11, Siglec-11, Sialic acid-binding Ig-like lectin 11, Sialic acid-binding lectin 11

规格

20ug
50ug
100ug
200ug
1mg

DATASHEET MSDS

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产品介绍

Catalog Number	KRP007
Alias	唾液酸结合免疫球蛋白样凝集素11, Siglec-11, Sialic acid-binding Ig-like lectin 11, Sialic acid-binding lectin 11
Size	20ug, 50ug, 100ug, 200ug, 1mg
Product Description	Human Siglec-11(Asn17-His543(Glu84Ala &Lys145Gln))
Molecular Name	Siglec-11
Product Introduction	Siglec-11属于免疫受体家族，参与调节免疫细胞的功能，尤其在大脑内有重要作用。
Molecular Weight	110-135 kDa
Expression System	HEK293F Cells
Species	Human
Concentration	联系销售经理获得最新批次的浓度
Purity	≥90%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	Q96RL6
Storage Condition	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation	Supplied in PBS
Shipping Condition	This product is shipped on ice packs or dry ice.
Background	Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.
Endotoxin	< 0.1 EU per ug
Biological Activity	Measured by its binding ability in a functional ELISA. When Recombinant Human Siglec‑11 Fc Chimera is immobilized at 2 µg/mL (100 µL/well), it binds Biotinylated Recombinant Human Siglec‑15 Fc Chimera Avi-tag protein with an ED50 of 0.7- 4.2 μg/mL.
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。