Recombinant Human NCR1 Protein, C-hFc tag
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产品编号
KRP005
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别名
自然杀伤细胞受体1, NCR1, Nuclear receptor corepressor 1, N-CoR, N-CoR1
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KRP005 |
| Alias | 自然杀伤细胞受体1, NCR1, Nuclear receptor corepressor 1, N-CoR, N-CoR1 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Human NCR1(22-254 aa) |
| Molecular Name | NCR1 |
| Product Introduction | 在自然杀伤细胞(NK细胞)中表达，参与免疫监视和抗肿瘤免疫。 |
| Molecular Weight | 60-80 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE | |
| Purification | Affinity Purification |
| Uniprot ID | O75376 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Mediates transcriptional repression by certain nuclear receptors (PubMed:20812024). Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. Participates in the transcriptional repressor activity produced by BCL6. Recruited by ZBTB7A to the androgen response elements/ARE on target genes, negatively regulates androgen receptor signaling and androgen-induced cell proliferation (PubMed:20812024). |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its ability to bind Recombinant Human Vimentin in a functional ELISA with an estimated KD < 2 nM. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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