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Recombinant Human IL28A Protein, C-His Tag

Recombinant Human IL28A Protein, C-His Tag

产品编号

KRP001

别名

白细胞介素28A, IL28A, Interferon lambda-2, IFN-lambda-2, Cytokine Zcyto20, Interleukin-28A, IL-28A

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberKRP001
Alias白细胞介素28A, IL28A, Interferon lambda-2, IFN-lambda-2, Cytokine Zcyto20, Interleukin-28A, IL-28A
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionHuman IL28A(Val26-Val200)
Molecular NameIL28A
Product Introduction在抗病毒免疫反应中发挥重要作用,调节免疫系统的活动。
Molecular Weight20-23 kDa
Expression SystemHEK293F Cells
SpeciesHuman
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
SDS-PAGE
PurificationAffinity Purification
Uniprot IDQ8IZJ0
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationSupplied in PBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundCytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1.
Endotoxin< 0.1 EU per ug
Biological ActivityMeasured in an anti-viral assay using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus. The ED50 for this effect is 5-30 ng/mL.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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