| Catalog Number | KMPH854 |
| Alias | Toll 样受体 2；Toll like receptor 2; Toll like receptor 2 precursor; Toll-like receptor 2; TLR 2; TLR2; TLR-2; Toll/interleukin-1 receptor-like protein 4; CD282 antigen; CD282; TIL 4; TIL4 |
| Size | 100ug |
| Product Description | The Recombinant Human TLR2 Protein with His Tag (KMPH854) is expressed from E.coli. It contains 621-780 AA. |
| Molecular Name | TLR2 |
| Expression System | E.coli |
| Species | Human |
| Concentration | Batch to Batch |
| Purity | > 90% as determined by SDS-PAGE |
| Purification | Affinity Purification |
| Storage Condition | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Formulation | 0.01 M PBS, pH 7.2-7.4 |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | TLR2 (Toll Like Receptor 2), also known as CD282 or TIL4, is a Protein Coding gene12. It encodes a pattern recognition receptor that plays a fundamental role in innate immunity by recognizing pathogen-associated molecular patterns (PAMPs) from bacteria and other microbes3. Among its related pathways are the Toll-like receptor signaling pathway7. TLR2 is highly expressed in peripheral blood leukocytes, particularly in monocytes, and mediates host response to Gram-positive bacteria and yeast via NF-κB activation36. This gene acts through MYD88 and TRAF6 signaling adaptors to induce inflammatory cytokine production36. An important paralog of this gene is TLR47. |
| Predicted Molecular Weight | 23 kDa |
| Tag | N-His Tag |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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