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Recombinant Human EGFR Protein, His tag

Recombinant Human EGFR Protein, His tag

产品编号

KMPH7115

别名

表皮生长因子受体;Epidermal growth factor receptor; EGFR; ERBB; ERBB1; HER1

规格
  • 100ug
产品介绍
Catalog NumberKMPH7115
Alias表皮生长因子受体;Epidermal growth factor receptor; EGFR; ERBB; ERBB1; HER1
Size100ug
Product DescriptionThe Recombinant Human EGFR Protein with His Tag (KMPH7115) is expressed from E.coli. It contains 1071-1150 AA.
Molecular NameEGFR
Expression SystemE.coli
SpeciesHuman
ConcentrationBatch to Batch
Purity> 90% as determined by SDS-PAGE
PurificationAffinity Purification
Storage ConditionStore at -80°C. Avoid repeated freeze-thaw cycles.
Formulation0.01 M PBS, pH 7.2-7.4
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundAs a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.
Predicted Molecular Weight11 kDa
TagC-His Tag
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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