Recombinant human TRPV1 protein, His Tag_天津卡梅德科技发展有限公司

KMP4944

TRPV1, VR1, Transient receptor potential cation channel subfamily V member 1

DATASHEET MSDS

产品介绍

Catalog Number	KMP4944
Alias	TRPV1, VR1, Transient receptor potential cation channel subfamily V member 1
Size	50ug, 100ug, 200ug, 500ug
Product Description	Recombinant human TRPV1 protein, His Tag (KMP4944) is expressed from E.coli with his tag.It contains Met 1-Arg 433.
Molecular Name	TRPV1
Expression System	E.coli
Species	Human
Concentration	联系销售经理获得最新批次的浓度
Purity	>85% as determined by SDS-PAGE
Purification	Affinity Purification
Uniprot ID	Q8NER1
Storage Condition	Store at -80℃. Avoid repeated freeze-thaw cycles.
Formulation	PBS, pH7.4
Shipping Condition	This product is shipped on dry ice.
Background	TRPV1 (Transient Receptor Potential Vanilloid 1) is a non-selective cation channel belonging to the TRP superfamily, widely expressed in sensory neurons and non-neuronal tissues. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activated by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius. TRPV1 plays a central role in detecting and integrating thermal, chemical, and inflammatory pain signals, making it a critical target for pain management research.
Predicted Molecular Weight	50.9KD
Protein Vector	pET-28a（+）
Tag	His
Sequence	1-433AA
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。

FAQ

如何解读重组蛋白的产品说明书？

（1）来源/表达系统：决定了蛋白的修饰类型。（2）标签信息：位置（N端/C端）和类型，可能影响蛋白功能。（3）内毒素水平：对于细胞实验尤为重要，通常要求 < 1.0 EU/μg，敏感细胞（如原代细胞、干细胞）要求 < 0.1 EU/μg。（4）浓度和缓冲液成分：确保与您的实验体系兼容（例如，避免高浓度咪唑或β-巯基乙醇干扰）。（5）生物活性数据：通过细胞增殖抑制试验、ELISA结合试验、酶动力学分析等验证，是判断蛋白功能是否正确的关键。

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